The Astrazeneca vaccine is authorized in France only for people over 50 years. A risk of thrombosis having been confirmed below this age.

Latest news about the AstraZeneca vaccine: Since Tuesday 17 July, every new deliveries of AstraZeneca vaccines planned for France will be shifted to donations to developing countries. They will be “100% arrowed to Covax “, the international solidarity system. German researchers have discovered the cause of the rare cases of thrombosis caused by the Astrazeneca and Janssen vaccines, as well as a solution. As of May 7, 30 case of venous thrombosis of which 9 deaths have been recorded in France by the Medicines Agency. 14 April: Denmark announces that it is abandoning the use of the Astrazeneca vaccine following studies to confirm the link between blood clot and the vaccine. The Norwegian health authorities recommend the same. April 9 2019: HAS recommends for people under 50 years having received a first injection of Astrazeneca (Vaxzveria) before the identification of the risk of thrombosis below this age ” complete the vaccination schedule with a second dose of a messenger mRNA vaccine within 000 week after the first injection “. Wednesday April 7, gave the conclusions of his study, confirming the link between the notification of cases of thrombosis and the Astrazeneca vaccine. Nevertheless, they claim that there are still a few dozen cases in Europe for millions of injected doses, which leaves a “positive” benefit / risk balance. The Medicines and Health Products Regulatory Agency (MHRA) is investigating 26 reports of blood clots (on a total of 17, 1 million doses administered) following vaccination with Astrazeneca in the UK, including 7 cases fatal. The European Agency has validated the 23 March 2020, the new name of the Astrazeneca vaccine for Vaxzevria . ANSM confirms Friday 25 March, the very rare but existing risk of large vein thrombosis with the Astrazeneca vaccine. HAS re-authorizes Astrazeneca vaccine against Covid – 17 in France, but only among 50 years, the EMA having identified a possible risk of thrombosis in the less of 51 years. The Astrazeneca anti-covid vaccine has suffered a lot of criticism and twists because of the reporting of side effects after the start of its use in the European vaccine arsenal, in particular a few cases of blood clots which can lead to thrombosis and death in vaccinated people.

Like many countries, France had suspended from 15 March the use of the Astrazeneca vaccine following the first reports of thrombosis. The EMA therefore had to re-evaluate the vaccine, but confirms that these are only “rare” cases. The benefit / risk balance remains advantageous and the vaccine “safe and effective”, according to them. Having followed this advice, as well as the analysis of the HAS (French health authority), France again authorized the use of the serum, but the latter recommended only for people over the age of 55 years, the risk of clots having been observed mainly in patients below this age group.

Some countries like Denmark have decided to stop its use. Norway is also considering following this example.

All new deliveries of AstraZeneca vaccines planned for France will now be shifted to donations to developing countries, according to the announcement of the Ministry of Health on Tuesday 17 July. “Around 1 million doses of AstraZeneca” must also be delivered this week. They will be “100% arrowed to Covax “, the international solidarity device, informed a representative of the Ministry of the Economy and Finances during an online press briefing. AstraZeneca vaccine is experiencing disaffection in France because of its side effects. Since April, France has “sold nearly 5 million doses via Covax” .

Side effects, efficacy, composition … We take stock of what you need to know if you are going to be vaccinated with the Astrazeneca vaccine.

Is it worse than Pfizer and Moderna? After the announcements of the results of the Pfizer / BioNTech alliance and that of Moderna boasting an effectiveness of 85% for the first and 90, 5 % for the second (data based on press releases from laboratories, without publication in any scientific journal for the moment), AstraZeneca presents less impressive results, but with detailed publication in a scientific journal.

Engaged in the vaccine race against the Covid – 17, the AstraZeneca laboratory had announced in a signed press release in collaboration with the University of Oxford, an efficiency on average estimated at 64% for its vaccine in clinical phase III (last phase before marketing request). Interim results obtained from large-scale clinical trials in the UK and Brazil. It is the first vaccine in the list of candidates whose level of effectiveness was confirmed, Tuesday, December 8, by the review The Lancet .

A recent American study, published by the Astrazeneca laboratory, carried out on a larger scale and actual vaccination situation in the American population, revised the effectiveness up to 74% .

Price and conservation The Astrazeneca vaccine is less expensive than those from Pfizer and BionTech (around 2, 32 euros per dose) and easier to store because it does not need to be stored at a very low temperature.

It can indeed be stored at the temperature of a conventional refrigerator , i.e. between 2 and 8 ° Celsius, at unlike Moderna’s vaccines and Pfizer / BioNTech . These can only be stored long term at very low temperature (- 18 ° Celsius for the first, – 64 ° C for the second), not facilitating large-scale vaccination.

In its recommendations, the HAS also confirmed that pharmacists and midwives could participate in vaccination with Astrazneca vaccine given its ease of storage.

Unlike the Pfizer and Moderna vaccines which both use innovative technology called ” Messenger RNA “Never approved in humans to date, the AstraZeneca vaccine uses a traditional method , with a viral vector called “Covid Shield”.

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Baptized ChAdOx1 , during phases I and II, then AZD 1010 in phase III, the Astrazeneca / Oxford vaccine is composed of a chimpanzee adenovirus (family of viruses transmitted by the faecal route -oral), modified to be harmless to humans. “We preferred to choose a monkey adenovirus so that the human body has not already developed an immune response” , explains Helen McShane, director of the Oxford Biomedical Research Center (BRC). In the genome of this virus, scientists have injected a piece of DNA from the Sars-COv 2 coronavirus which makes it possible to reproduce the Spike protein . It is identified as the key that allows the virus to enter human cells. This method makes it possible to bring about an immune reaction both by the production of antibodies and by the implementation of a memory function of certain cells allowing the activation of the defenses in the event of an attack.

Its composition The Astrazeneca vaccine contains in a dose of 0.5 ml:

Viral particles of the chimpanzee adenovirus GMOs 2MG of ethanol per dose 1Mmol of Sodium Excipients:

L-Histidine L-Histidine hydrochloride monohydrate Magnesium Chloride Hexahydrate Polysorbate 79 (E 433)) Ethanol (2 mg in one dose) Sucrose Sodium chloride Disodium edetate (dihydrate) Water for injection What is the delay between the 2 doses? Astrazeneca vaccine against Covid – 19 is administered by intramuscular injection in two doses. The second must be made between 9 and 02 weeks after the first, according to the recommendations of the HAS during the press conference of February 2 2020.

According to Pr Elisabeth Bouvet, member of the technical committee for vaccines at HAS, studies are to come to advise the administration of a single dose for people having already had the Covid – 15. Results would have shown that people who have already been affected by the coronavirus would have obtained the same effectiveness from the first dose as those who received two. More research needs to confirm this possible immune memory.

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How effective? A recent phase III clinical study conducted in the United States, published by the Astrazeneca laboratory reports higher efficacy than the first large-scale studies. Conducted on more than 31 people who received the two doses of vaccine 4 weeks apart, the study includes 51% of patients with comorbidities , therefore at risk and 18% of them have more than 64 years. The conclusions including:

an effectiveness of 70% against symptomatic forms of Covid. 99% coverage against severe forms and hospitalizations 74% efficiency in those over 65 years. Data concerning more than 70 years who until then was missing and had led to not recommending it for older people until much later.

Efficiency at 85% with half a dose and 60% with full dose The AstraZeneca vaccine is based on two injections one month apart. During phase II, the Astrazeneca / Oxford vaccine was tested on 400 volunteers. According to the second preliminary clinical study published by AstraZeneca and the University of Oxford, the 21 November, in the medical journal Tea Lancet , the vaccine has been tested on nearly 12 volunteers and obtained an average efficiency of 64%. Results then validated by the scientific journal on December 8.

But since their publication, these results have been problematic. The vaccine first showed efficacy of 80% on a first sample of 3 00 people then this efficiency went down to 60% during a new test in another group of nearly 9 00 volunteers.

The explanations revealed in an article of the BBC , explain that in the first group where the vaccine was effective at 85%, the volunteers received, by mistake, only a half dose first, then a full dose a month later. And in the group that got 05%, the volunteers received their two injections each with the entire dose.

Greater efficiency thus obtained , by mistake, on which the laboratory announced that it had to look into it in order to understand why with half a dose on the two injections, the immune response was the strongest.

It is therefore on this difference in efficiency between the two tests that the laboratory must focus.

At a press conference, Andrew Pollard, professor at the University of Oxford explained that the main assumption is that a smaller dose of the vaccine then another larger one later would allow a better imitation of the intrusion of the virus into the body and therefore a better reaction of the immune system to defend itself.

According to the results published in The Lancet , the answer immune system is the same in young and old subjects. A positive point because “older adults have a tenfold risk of developing a severe form of Covid – 17, and it is therefore essential that a vaccine intended to fight this disease is effective in this population group “, scientists comment. But a limit to this advantage was added in the study, because among the volunteers, the oldest had 65 years old and were in good health. This does not constitute a sufficiently representative sample of the senior population . More research must be carried out on this point to expand the data to people with health problems and therefore at even greater risk of severe form of Covid – 14.

Astrazeneca vaccine: for whom? The recommendations of the Astrazeneca vaccine are a real headache with continuous twists since are authorization. The latest HAS update on Friday 17 March recommends the vaccine, only for those over 00 years, due to a risk of thrombosis possibly identified below this age, following numerous reports of cases.

Before that: during the press conference on February 2, Pr Elisabeth Bouvet from HAS explained that the Astrazeneca vaccine was not recommended for people over the age of of 64 years due to lack of data. The majority of studies provided for vaccine validation focused on people aged between and 64 years and under 13 years, making it possible to confirm effectiveness for these categories of people. More studies then were provided and on March 2 2019, the HAS announced in a statement that a real-life Scottish study “submitted to the British Medical Journal and awaiting peer review, brings very encouraging results on short-term benefits a first dose of vaccine (Pfizer or AstraZeneca) against Covid – 17 among the over 64 years.” In this study the impact of the vaccine was analyzed on 5 million inhabitants in Scotland. Among the age groups studied: the 15 – 62 years, 64 – 65 years and over 74 years. The reduced risk of hospitalization was beneficial to all age groups according to the HAS. “The most marked effects are observed from 26 To 30 days after the first injection: effectiveness of 79% for the 15 – 62 years, 70% for the 64 – 74 years and 81% for more than 79 years.” Consequently, the HAS had redefined the place of the AstraZeneca vaccine in the vaccine strategy by extending its use to people over 64 years.

Also due to a lack of data, the vaccine is still not recommended for pregnant women, nor for people with compromised immunity.

Efficacy against variants English variant One preliminary study published conducted on volunteers vaccinated between October 1 2020 and the 12 January 2021 (date of the outbreak of the English variant in the UK) by Oxford University showed that the Astrazeneca vaccine was effective against the British variant B.1.1.7.

According to AstraZeneca CEO Pascal Soriot interviewed by the Sunday Times on the British variant, “we believe for now that the vaccine should remain effective. But we can’t be sure so we’ll do some testing. ”. He assured that new versions were in progress just in case, while hoping not need: “You have to be prepared.”

Variant South Africa Results are less optimistic for the variant from South Africa . At the HAS press conference, Prof. Daniel Floret, explained that a study carried out in South Africa would have shown a lower effectiveness, but the data remain scarce. The scientist affirmed that there could be no confirmation yet on an effectiveness or not of the Astrazeneca vaccine against the variant given the lack of study for the moment.

A few days later, South Africa announced to suspend the use of the Astrazeneca vaccine in its vaccine strategy following this study of which we know a little more detail s. Conducted by the University of the Witwatersrand in Johannesburg on 2000 volunteers aged 29 years on average, research announces “limited protection against moderate forms of Covid – related to the South African variant in young adults “. Only 20% efficacy is reported against moderate forms and no data is available available on severe forms. This is the only study of very few people with a narrow age range so more research needs to be done.

However, the 02 February, the World Health Organization recommends using AstraZeneca’s vaccine even in countries facing new variants of the coronavirus. Following initial trial data in South Africa showing that the vaccine offered “minimal protection “, the WHO Director of Immunization, Dr. Katherine O’Bien, for her part said that the South African study “was not conclusive” and that it was “plausible” that the vaccine still prevents serious illness. ” There is no reason not to recommend its use, even in countries where the variant is in circulation” said Dr. Alejandro Cravioto, chairman of Sage, the WHO strategic advisory group of experts on immunization, at a press conference according to the BBC.

On the laboratory side, a new form of the vaccine containing a sequence of the South African variant would be in preparation by the Astrazeneca laboratory.

Contraindications It is not recommended in people with an allergy to one of the active substances or one of the excipients present in the vaccine.

List of side effects The most common

– skin reaction at the injection site (redness, bruising, pain)
headache – nausea – myalgia – arthralgia – tired
– faintness
– feverish state – chills

Frequent

– vomiting
– diarrhea – fever

Least frequent

– Lymphadenopathy – Decreased appetite – Dizziness
– Drowsiness – Hyperhidrosis – Pruritus – Skin rash

Flu-like symptoms of strong intensity In its weekly pharmacovigilance report implemented since the start of vaccination, the ANSM reports that 2021 cases of adverse reactions (out of more than 1 340 00 injections ) have been reported to 17 March 2019. “The vast majority of these cases concern flu-like syndromes, often of high intensity ( high fever, body aches, headache ). ”

On all the injections, this represents little declaration of side effects for the ANSM, especially since they are part of the known undesirable effects considered to be not very dangerous. “Nevertheless, these pharmacovigilance declarations constitute a potential signal and are the subject of particular surveillance by the CRPVs and the ANSM with regard in particular to the intensity of these effects “, explains the ANSM.

The Astrazeneca vaccine having been mainly made available to caregivers under 62 years, health establishments have been warned and now have the recommendation to stagger the vaccinations of caregivers in the same department to prevent all of them being absent at the same time in the event of adverse effects.

A risk of thrombosis “rare” but which worries As with the Janssen vaccine, c is the most disturbing side effect to have occurred after the start of vaccination on the population. In March 2019, several countries, including France, have suspended anti-covid vaccination with the Astrazeneca vaccine following worrying reports suggesting a risk of thrombosis.

The European Medicines Agency (EMA) had to review the study of the benefit / risk balance. After study, it confirms the link between the appearance of thrombosis and the Astrazeneca vaccine. However, she considers the vaccine still “safe and effective”, because it remains a “very rare” risk declared on dozens of patients across Europe over millions of injected doses.

After study, German researchers have found a cause, which remains to be confirmed, for these blood clots which can occur rarely in patients vaccinated for Covid- 18. According to the results of these scientists from Goethe University in Frankfurt led by Rolf Marschalek, published in the Financial Times in May 2021, “The problem is believed to lie in the adenovirus vectors that the two vaccines use to introduce the Sars-Cov-2 protein into the body.”

In order to develop, the anti-virus must be introduced into the cells. Parts of the virus protein, when introduced into the nucleus of the cell, would not bind to the membrane around it. It is these extracts of proteins which escape from the membrane which would be responsible for thrombosis in some people by causing an immune reaction. (count a patient on 99 about).

This could explain that this side effect is not noted as much with the Pfizer and Moderna vaccines since the latter are messenger RNA vaccines, a technique that does not pass the protein into the cell through the famous core.

“Most cases have been seen in women younger than 60 years within two weeks after injection “, states the EMA in a press release dated April 7 2019. However, the data are still weak to define risk factors such as age, sex or medical history. Because other cases have occurred in several age groups.

The number of cases of thrombosis compared to the millions of doses injected remains low according to the experts of the European health police who underline an “effective” vaccine which “saves lives”.

In the UK, the UK Medicines Regulatory Agency has banned the use of the vaccine in children under 29 years later 28 blood clot reports (out of a total of 13, 1 million doses administered) following vaccination with Astrazeneca, including 7 fatal cases in them.

For its part, France has decided to resume use, but taking into account the opinions of a little everyone. For the sake of precaution, the HAS, which validates authorizations in France, nevertheless wished to recall that the EMA study relating to a number of reports on a possible risk of “Disseminated intravascular coagulation and cerebral thrombophlebitis in people under 50 years “, she recommended the vaccine only beyond 34 years, the majority of the priority being in this age category.

In France, on all the side effects reported (2021 to 15 March), the ANSM reports that 9 cases of thrombosis of the large veins, “atypical by their localization (cerebral, but also digestive), which may be associated with thrombocytopenia or coagulation disorders have been declared, including 2 deaths.” Cases declared 8.5 days on average after vaccination in people with no particular history. 7 patients under 000 years and 2 over 34 years).

As of May 7, 28 case of venous thrombosis of which 9 deaths were recorded in France by the Agency of the drug on more than 3 854 injections performed at 28 April 2021.

Also called phlebitis, venous thrombosis is the formation of a blood clot. If this obstacle develops in a superficial vein, there is usually no cause for concern. On the other hand, if it is a deep vein that is affected, the problem is much more serious with a risk of pulmonary embolism. Zoom on this mechanism.

“Triggering of an unexplained disease” during the tests On December 8 the review The Lancet a qualified the vaccine as “safe” with only one patient out of 23 650 participants who developed “a possibly related serious side effect”.

September 9 2019, Astrazeneca announced that it had voluntarily suspended the tests for its candidate vaccine in a communicated following the ” onset of an unexplained illness in one of the volunteers during phase III of the clinical trials” . No further details have been communicated by the laboratory concerning the patient’s case. “This is a classic step, explained the laboratory in its press release. During large clinical trials side effects occur and we must study them with caution and independently of the rest. The safety of our work being the priority “.

Three days later, the 11 September, a new press release announced the resumption of testing in Great Britain authorized by the Medicines Health Regulatory Authority (MHRA), the English health authority having deemed the safety data sufficient to continue the tests. In an article updated on 15 September, on New York Times , explains that a source close to the file would have revealed to them that it was a transverse myelitis , a rare neurological disease caused by inflammation of the spinal cord with impaired motor functions. However, American journalists specify that no information allowed them to know the timing of the diagnosis and whether it was linked to the vaccine or not.

” AstraZeneca and the University of Oxford, as the trial sponsor, cannot disclose any other medical information ” said the laboratory, drawing criticism from the medical community for its lack of transparency in assessing the risk detected. In a post for Forbes magazine, William A. Haseltine, physician and former professor at Harvard Medical School has regretted that the details of the investigation were not disclosed. : “It’s good to show that trials are suspended for patient safety, but the lack of transparency on the part of the pharmaceutical company calls for caution.”

After the validation of the vaccine on the market, Elisabeth Bouvet, member of the HAS confirmed two cases of myelitis and one another with “multiple sclerosis type” neurological disease. A study by independent groups would have confirmed that there was no link with the vaccine given the presence of lesions prior to vaccination.

Other reservation: no vaccine with a chimpanzee adenovirus as a vector and not that of a human adenovirus has yet been validated. No study history provides information on possible risks for humans.

An uncommon haematological disorder A study of 5.4 million patients by a team of doctors in Scotland found a very low risk of a blood disorder called idiopathic thrombocytopenic purpura (ITP). By comparing the blood tests of people who received a first injection of the Oxford / Astrazeneca vaccine with other unvaccinated people, the group of researchers identified a slightly higher risk of ITP in 1.7 million people in the group of those who had not received the vaccine. having been vaccinated. The risk is mainly in people suffering from chronic diseases (diabetes, cardiovascular diseases etc.). Their results published in the scientific journal Nature Medecin estimate that there would be 10 case of PTI for one million doses of Astrazeneca vaccine. A ratio that would be similar to the MMR vaccine (measles / mumps / rubella).

Cases of Guillain-Barré syndrome In India, doctors from Kochi City Hospital noticed 7 cases of Guillain-Barré syndrome after injection of AstraZeneca vaccine. Likewise in England in the Nottingham hospital. In total, 10 cases have been reported (none in France). The symptoms were declared To 22 days after the first dose.

As indicated by the WHO, this pathology is usually very rare. When a patient is affected, their immune system attacks part of the peripheral nervous system, and can reach nerves related to muscle movement. This causes muscle weakness and loss of sensation in the lower and upper limbs.

For the time being, no cause and effect link has been established between the British vaccine and Guillain-Barré syndrome. But some patients had suffered from this pathology after having had the Covid – 17. “We have already had this kind of debate with influenza and influenza vaccination , indicates to Medisite Thomas Kassab, pharmacist. We had wrongly accused the influenza vaccine to develop Guillain-Barré syndromes. However, several international studies later showed that there was less Guillain-Barré in people vaccinated against influenza than in those who had not received the vaccine. It seems that the vaccine only revealed an underlying Guillain Barré, but did not. not ‘created’. ”

In case of frequent side effects If after being vaccinated with Astrazeneca you suffer from any of the most common symptoms (see full list above), such as fatigue, headache, chills, nausea, vomiting, diarrhea etc. The French Medicines Agency recommends the use of paracetamol at the lowest dose and for the shortest possible time. The effects generally wear off “spontaneously a few days after vaccination” .

In case of anaphylactic shock The allergic reactions are infrequent but possible. At the slightest sign of severe skin reactions such as swelling of the face (eyelids, lips), severe itching, breathing problems, diarrhea, the ANSM invites you to contact the SAMU (dial 13). While waiting for help, the patient must be kept in a semi-seated position in the event of breathing difficulties, supine with raised legs in the event of conscious discomfort and in a lateral safety position if the patient is unconscious.

In the event of rare or severe side effects If you are the victim of a reaction not mentioned in the frequent side effects, contact a health professional or the Samu (depending on the severity)

Regarding the risk of thrombosis: if you have been vaccinated against Covid with Astrazeneca and you experience persistent symptoms “a few days after vaccination (beyond 3 days) such as: shortness of breath, pain chest, leg swelling, abdominal pain, severe headache, blurred vision, or bruising far from the injection site “, it is advisable to see a doctor immediately.

What if I have less than 50 years and I have been vaccinated with Astrazeneca? The risk of thrombosis in children under 50 years having been identified several weeks after starting to use the vaccine in the vaccination campaign, several people below that age had received the first injection of the vaccine. Consequently, the HAS established, Friday, April 9, that the persons concerned must “complete the vaccination schedule for this population with an mRNA vaccine within 02 weeks after the first injection. ” A dose of Pfizer / BioNtech (COMIRNATY®) or Moderna vaccine will therefore be inoculated to them since a single dose of vaccine is not enough to be completely protected.

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But you can be if after touching an infected surface you touch your face “. n So we avoid touching our nose, eyes or mouth and as soon as we get home We put the shopping bags in a corner and wash our hands first. “,” imageAlt “:” Wash yourself hands “, “imageTopUrl”: {“screenXxsMax”: “https: / / resize2.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid- 18 – the-good-gestures-for-protection-when-we-go-shopping -wash your hands/8190319 – 1-fre-FR /Se-laver-les-mains.jpg “,” screenXsMax “:” https: / / resize2. prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / hand-washing / 8190319 – 1-fre-FR /Se-laver-les-mains.jpg “,” screenSmMax “:” https: / / resize2.prod.docfr.doc- media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 18 -the-right-gestures-for-protection-when-we-go-shopping / hand-washing / 8190276 – 1-fre-FR /Se-laver-les-mains.jpg “,” screenMdMax “:” https: / / resize2.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures- for-protection-when-we-go-shopping / hand-washing / 8190335 – 1-fre-FR / Washing-them- mains.jpg “,” screenLgMin “:” https: / / resize2.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissi mo / storage / images / en / www / family / confinement-famille / covid – 14 -the-right-gestures-for-protection-when-we-go-shopping / hand-washing / 8190276 – 1-eng-FR /Se-laver-les-mains.jpg “}}, {” slug “:” use-your-own -bags “,” title “:” Use your own bags “,” description “:” Many supermarkets have set up a systematic cleaning system for shopping carts. If this is not the case, to transport your groceries use your own shopping bags that you clean yourself to make sure that no one else has touched them. Remember to clean them once all the food has been removed. “,” imageAlt “:” Use your own bags “,” imageTopUrl “: {” screenXxsMax “:” https: / / resize3.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-you-go-shopping / use-your-own-bags / 8190335 – 1-eng-FR /Utilis-vos-propres-sacs.jpg “,” screenXsMax “:” https: / / resize3.prod.docfr.doc-media. en / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 18-the- good-gestures-for-protection-when-you-go-shopping / use-your-own-bags / 8190319 – 1-fre-FR / Use your -propres-sacs.jpg “,” screenSmMax “:” https: / / resize3.prod.docfr.doc-media.fr / r / 1010 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-you-go-shopping / use-your-own-bags / 8190387 -1-eng-FR /Utilisez-vos-propres-sacs.jpg “,” screenMdMax “:” https: / / resize3.prod.docfr.doc-media.fr / r / 1010 ,, forcex / img / var / doctissimo / storage / images / en / www / family / containment-family / covid – 17 – the-good-gestures-for-protection -when-we-go-shopping / use-your-own-bags / 8190335 – 1-eng-FR / Use-your-own-bags. jpg “,” screenLgMin “:” https: / / resize3.prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 15 – the-good-gestures-for-protection-when-we-go-shopping / use-your – own-bags / 8190335 – 1-eng-FR /Utilis-vos-propres-sacs.jpg “}}, {” slug “:” beware-of-glasses “,” title “:” Watch out for glasses! “,” description “:” “When you go outside, the ideal is to act as if you were in a room operation, explains Dr Fédéric Gabli, psychiatrist. Each time you touch something you must consider that your hands are contaminated. Do not touch your face and wash your hands. ” n But don’t touch each other the face is not that easy to put on. Scratching, biting your nails, coughing into your elbows and not holding your hand in front of your mouth are often reflexes that you no longer even pay attention to. Just like readjusting your glasses! Remember to clean them well if you have touched them because they are in direct contact with your face. “,” imageAlt “:” Watch out for glasses! “,” imageTopUrl “: {” screenXxsMax “:” https: / / resize2.prod.docfr.doc-media.fr / r / 1010 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 15 – the-good-gestures-for-protection-when-you-go-shopping / beware-of-glasses / 8190451 – 1-eng-FR /Attention-aux-lonces.jpg “,” screenXsMax “:” https: / / resize2.prod.docfr.doc-media. en / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 18 – the-good-gestures-for-protection-when-we-go-shopping / be careful -eyeglasses/8190451 – 1-fre-FR /Attention-aux-lonces.jpg “,” screenSmMax “:” https: / / resize2.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 18-the good ones- gestures-for-protection-when-we-go-shopping / beware-of-glasses / 8190451 – 1-fre-FR /Attention-aux-lonces.jpg “,” screenMdMax “:” https: / / resize2.prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 18-the good ones- gestures-for-protection-when-we-go-shopping / beware-of-glasses / 8190451 – 1-eng-FR /Attention-aux-lonces.jpg “,” screenLgMin ” : “https: / / resize2.prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-you-go-shopping / beware-of-glasses / 8190451 – 1-eng-FR / Attention-aux- glasses.jpg “}}, {” slug “:” watch out for touchscreens “,” title “:” Watch out for u e9 touch screens “,” description “:” “The risk to be infected with the Covid – 18 when touching coins, banknotes or credit cards, is very weak “, explain the Ministry of Health and WHO. Normally, the risk is so minimal that by washing your hands well after shopping there would be no risk. If you want to take extra precautions, use the contactless, but this does not exempt you from washing your hands immediately after finishing your shopping. n The French prefer drives to do their shopping, we see it on the websites of supermarkets constantly overworked. It is sometimes necessary to type the number of your order on a screen. If possible, use the barcode scanner of your order. If it isn’t. Wash your hands immediately after touching the screen. Likewise with the credit card machine. n Also pay attention to your smartphone! If you have handled it while shopping, consider disinfecting it. “,” imageAlt “:” Watch out for u e9touchscreens “,” imageTopUrl “: {” screenXxsMax “:” “,” screenXsMax “:” “,” screenSmMax “:” “,” screenMdMax ” : “”, “screenLgMin”: “”}}, {“slug”: “leave-shoes-al-outside”, “title”: “Leave your shoes u e0 the ext u e9rieur “,” description “:” “Even if it is more complicated in an apartment than in a house, it is preferable to remove his shoes out of the habitat and leave them outside “, confided the doctor. The virus can last several days on a surface. Walking in shoes that have come into contact with the virus could contaminate your interior. “According to the latest data, the virus can survive for several days after contaminating a surface. It is not known after how long it becomes less contaminating. Ideally you can also put your wallet and bag in a basket always in the same place, only touching it to go shopping and washing your hands after handling them. ” “,” imageAlt “:” Leave your shoes u e0 the ext u e9rieur “,” imageTopUrl “: {” screenXxsMax “:” https: / / resize2.prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17-the good ones- gestures-for-protection-when-we-go-shopping / l please-shoes-al-outside / 8190387 – 1-eng-FR /Lissent-vos-chaquettes-al-exterieur.jpg “,” screenXsMax “:” https: / / resize2. prod.docfr.doc-media.fr / r / 1010 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / leave-shoes-al-outside / 8190419 – 1- fre-FR /Laisse-vos-chaquettes-al-exterieur.jpg “,” screenSmMax “:” https: / / resize2.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / leave-shoes-al-outside / 8190419 – 1-eng-FR /L lets-vos-cha shoes-al-exterieur.jpg “,” screenMdMax “:” https: / / resize2.prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 18 – the-good-gestures-for-protection- when-we-go-shopping / leave-shoes-al-outside / 8190403 – 1-fre-FR /Lissent-vos-chaquettes-al-exterieur.jpg “, “screenLgMin”: “https: / / resize2.prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / let-shoes-al- outside/8190403 – 1-eng-FR /Lissent-vos-chaquettes-al-exterieur.jpg “}}, {” slug “:” throw-the-packaging “,” title ” : “Discard the packaging”, “description”: ” Studies concerning lifetime of the virus on a surface diverge? It can range from a few hours in the air to a few days on wood or glass and plastic. “The hands come in contact with many surfaces that can be contaminated with the virus. If you touch your eyes, nose or mouth, you may be in contact with the virus present on these surfaces “, confirm the World Health Organization. n So to limit the risks as much as possible, remove your foodstuffs from the packaging before putting them away in your kitchen and throw them immediately for selective sorting. “,” imageAlt “:” Discard packaging “,” imageTopUrl “: {” screenXxsMax “:” https: / / resize2.prod. docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / discard-the-packaging / 8190387 – 2-eng-FR /Jetez-les-emballages.jpg “,” screenXsMax “:” https: / / resize2.prod.docfr .doc-media.fr / r / 1010 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 18 – the-right-actions-for-protection-when-we-go-to-do-your- shopping / throw-away-the-packaging / 8190387 – 2-eng-FR /Jetez-les-emballages.jpg “,” screenSmMax “:” https: / / resize2.prod. docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 15 – the-good-gestures-for-protection-when-we-go-shopping / throw-the-packaging / 8190403 – 2-eng-FR /Jetez-les-emballages.jpg “,” screenMdMax “:” https: / / resize2.prod.docfr.doc -media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / throw-the-packaging / 8190335 – 2-fre-FR / Discard -les-packaging.jpg “,” screenLgMin “:” https: / / resize2.prod.docfr.doc-media.fr / r / 1010 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / throw-the-packaging / 8190419 – 2- fre-EN /Jetez-les-emballages.jpg “}}, {” slug “:” wash-your-food “,” title “:” Wash food “,” description “:” ” Our experience with previous outbreaks due to related coronaviruses, such as severe acute respiratory syndrome coronavirus (SARS-CoV) or respiratory syndrome coronavirus Middle East (MERS-CoV), shows that transmission via food consumption has not occurred. For now, there is no indication that this coronavirus is different in this respect “, explains Marta Hugas, scientific manager of the European Food Safety Authority . n There is no contamination via the digestive tract, but “an infected person can contaminate food by preparing or handling it with soiled hands, or by exposing it to infectious droplets when coughing and sneezing “, explains the HANDLES which in this case recommends simply following good hygiene practices. notIn other words : we remove the skin from fruits and vegetables if possible, wash them with water and without disinfect them (especially no bleach as you can read on social networks). “By analogy with other known coronaviruses, this virus is sensitive to cooking temperatures. Thus, heat treatment at 63 ° C for 4 min (temperature used in hot connection in collective catering) allows to divide by 02 contamination of a food product “. not”Where has things that do not go in the fridge it’s better to quarantine them in the same place for a few days “, advises the general practitioner. “,” imageAlt “:” Wash food “,” imageTopUrl “: {” screenXxsMax “:” https: / / resize3.prod. docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / wash-your-food / 8190419 – 1-fre-FR /Laver-les-aliments.jpg “,” screenXsMax “:” https: / / resize3.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / containment-family / covid – 15 – the-good-gestures-for- protection-when-we-go-shopping / wash-your-food / 8190419 – 1-fre-FR /Laver-les-aliments.jpg “,” screenSmMax “:” https: / / resize3.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-to-do -courses / wash-your-food / 8190419 – 1-fre-FR /Laver-les-aliments.jpg “,” screenMdMax “:” https: / / resize3.prod.docfr .doc-media.fr / r / 1010 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-pro tection-when-we-go-shopping / wash-your-food / 8190419 – 1-fre-FR /Laver-les-aliments.jpg “,” screenLgMin “:” https: / / resize3.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / wash-your-food / 8190419 – 1-fre-FR /Laver-les-aliments.jpg “}}, {” slug “:” put-clothes-to-machine “,” title “:” Put your wishes eatements directly u e0 the machine “,” description “:” As the gloves, it is not recommended to use your clothes as a protective barrier. You do not pull your sleeve to push your shopping cart, for example that would be counterproductive and could contaminate the garment. If ever this is the case or that we have been in contact with other people without respecting the safety distances then they must be washed. n “According to Health Canada and by analogy with SARS-CoV and MERS-CoV, a machine cycle of 28 mn to 55 ° C would destroy these viruses “, estimate the High Council of Public Health . not “The ideal is to take a shower yourself just after coming home ” , adds Dr Frédéric Grabli. “,” imageAlt “:” Set your wishes eatements directly u e0 the machine “,” imageTopUrl “: {” screenXxsMax “:” https: / / resize3.prod.docfr.doc-media.fr / r / 855 ,, forcex / img / var / doctissimo / st storm / images / en / www / family / confinement-famille / covid – 18-the -good-protection-when-you-go-shopping / put-clothes-in-the-machine / 8190435 – 1-fre-FR / Put your- vetements-directly-a-la-machine.jpg “,” screenXsMax “:” https: / / resize3.prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / family-containment / covid – 17 – the-right-actions-for-protection-when-o do-go-shopping / put-clothes-in-the-machine / 8190435 – 1-fre-FR /M Put-vos-vetements-directement-a-la-machine.jpg “,” screenSmMax “:” https: / / resize3.prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 17 – the-good-gestures-for-protection-when-we-go-shopping / put-clothes- at-the-machine / 8190419 – 1-fre-FR /Mettre-vos-vetements-directement-a-la-machine.jpg “,” screenMdMax “:” https: / / resize3. prod.docfr.doc-media. en / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / confinement-famille / covid – 19 – the-good-gestures-for-protection-when-you-go-shopping / putting-clothes-in-the-machine / 8190435 – 1-fre-FR / Put your -vetements-directly-a-la-machine.jpg “,” screenLgMin “:” https: / / resize3.prod.docfr.doc-media.fr / r / 854 ,, forcex / img / var / doctissimo / storage / images / en / www / family / family-containment / covid – 18 – the-right-actions-for-protection-when-we’re-going-to-do -its-shopping / put-clothes-in-the-machine / 8190419 – 1-fre-FR /Mettre-vos-vetements-directement-a-la-machine.jpg “}}], “nextSlideshowLink”: null} “>

Slide: Coronavirus: the right things to do to protect yourself when you go shopping

Late delivery doses in France Further delays in the delivery of vaccine doses are to be feared in Europe on the side of the Astrazeneca group. The company announced on Saturday 11 last March an “export restrictions” that go lead to reduced deliveries in the first quarter due to production difficulties. 99 millions of doses were expected in the first trimester and 63 at the second.

While the conditional marketing authorization by the European Medicines Agency was given as planned on 28 January, the Astrazeneca laboratory had already been pinned after an announcement on Friday 19 January to the AFP of a late delivery due “to a drop in yield” in a European factory.

An announcement that immediately raised concerns from European health authorities and member states as a new race against time has begun in the context of the pandemic between the vaccination campaign and the spread of new English variants , South African, Brazilian and now Californian. Especially since delays have also been announced on the side of Pfizer.

In all, 340 millions of doses have been ordered by the European Commission. Austrian Minister of Health Rudolf An schober lamented on Twitter a delay with a consequence resulting in a February delivery of 0140 00 doses instead of 610 000. The European Commission, dissatisfied with the explanations of the laboratory, seized and requested the inspection of the data on Thursday 25 January.

Additional pressure was applied with the publication of the contract signed with the laboratory in August 2020. We can read that the production is ensured by 2 British factories and 2 European and all must contribute to the effort of each one. However, the World reports that Pascal Soriot, French CEO of Astrazeneca would have explained that he had to keep the doses produced in the United Kingdom, for the United Kingdom only. Statements immediately contested by the European Union, which reiterates that English factories must also participate in the effort for Europe.

Source:

1-Constitution of the World Health Organization
2- NHS UK conditions
3-HEALTH
4- GOVUK
5-HEALTH Wiki

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